Protirelin

Protirelin specifically acts on the cells of the anterior pituitary gland. By binding to the corresponding receptors, it stimulates the pituitary gland to secrete thyroid - stimulating hormone (TSH), which in turn promotes the synthesis and secretion of thyroid hormones by the thyroid gland. It plays a crucial role in maintaining the normal function of the thyroid gland and the stability of thyroid hormone levels in the body. In the central nervous system, Protirelin can act as a neurotransmitter or neuromodulator, participating in the regulation of various neural activities, such as influencing the excitability of nerve cells and the release of neurotransmitters. It has a certain impact on brain development, cognitive function, and emotional regulation.

By injecting Protirelin and observing the response of TSH in the blood, it can help diagnose thyroid diseases such as hypothyroidism and hyperthyroidism, and identify whether the lesion is located in the thyroid gland, pituitary gland, or hypothalamus. It is used to evaluate the functional state of the anterior pituitary gland and determine whether there are lesions or functional disorders in the pituitary gland, which has certain auxiliary value in the diagnosis of diseases such as pituitary adenoma and hypopituitarism. It is also being explored for use in the treatment of some nervous system diseases, such as spinal cord injury and Parkinson's disease. It may play a certain therapeutic role by regulating the neuroendocrine function, improving the metabolism and function of nerve cells, etc.