Deslorelin

Deslorelin has a structure similar to endogenous GnRH and has a high affinity for GnRH receptors in the anterior pituitary gland. After binding, it can cause the release of pituitary gonadotropins (LH and FSH). Continuous use of deslorelin leads to the down - regulation of pituitary GnRH receptors, thereby inhibiting the secretion of gonadotropins and ultimately reducing the production of gonadal steroid hormones (such as testosterone, estrogen, etc.).

By inhibiting the secretion of testosterone, it can achieve the goal of inhibiting the growth of prostate cancer cells. It is one of the important drugs for the endocrine treatment of advanced prostate cancer. It can also inhibit ovarian function, reduce estrogen secretion, atrophy ectopic endometrial tissue, and relieve symptoms such as pain. For children with central precocious puberty, it can inhibit the function of the pituitary - gonadal axis, delay the development of secondary sexual characteristics, prevent premature closure of bones, and improve adult height.

In animal husbandry and wildlife management, it can be used to control the breeding cycle of animals, improve breeding efficiency, or induce estrus and ovulation in animals. It can be used for contraception in pet dogs, cats, etc. By inhibiting gonadal function, it can achieve the contraceptive effect and reduce accidental breeding of pets.