Hydroxytyrosol
English Name: Hydroxytyrosol
Molecular Formula: C₈H₁₀O₃
Molecular Weight: 154.1632
CAS Number: 10597-60-1
Appearance: Usually a white to light yellow crystalline powder.
It mainly exists in olives and their products, such as olive oil, olive leaf extract, etc. It also has a certain content in Plukenetia volubilis leaves.
Physiological Functions
Antioxidant: It can scavenge free radicals in the body, inhibit lipid peroxidation, reduce the production of malondialdehyde, and increase the activities of glutathione and superoxide dismutase. Its antioxidant capacity is stronger than that of vitamin E.
Anti-inflammatory: It can inhibit the activation of nuclear factor κB, reduce the expression of inflammatory cytokines, inhibit the activity of cyclooxygenase-2, and alleviate the inflammatory response.
Antitumor: It exerts its effects by inhibiting the proliferation of tumor cells, inducing apoptosis, and inhibiting angiogenesis. It can also enhance the sensitivity of tumor cells to chemotherapeutic drugs.
Hypolipidemic: It can reduce the levels of total cholesterol, triglycerides, and low-density lipoprotein cholesterol in plasma, and increase the level of high-density lipoprotein cholesterol.
Cardiovascular Protection: It can dilate the coronary arteries, increase myocardial blood flow, inhibit platelet aggregation, and prevent thrombosis. It can also lower blood pressure and improve arrhythmia.
Effects on the Skin: It can inhibit the activity of tyrosinase to reduce melanin production; inhibit the activity of senescence markers in human dermal fibroblasts after UVA irradiation, and combat photoaging; activate the longevity gene SIRT1, delay cell death, and promote the proliferation of collagen and elastin.
Application Areas
Food Field: As a natural antioxidant and preservative, it can prevent the oxidative rancidity of oils and fats, extend the shelf life of food, and improve the color and flavor of food.
Pharmaceutical Field: It is used to prepare drugs for anti-inflammatory, antioxidant, antitumor, and cardiovascular protection purposes. It can also be used as a pharmaceutical intermediate.
Cosmetics Field: When added to skin care products, it has the effects of antioxidant, whitening, anti-wrinkle, moisturizing, and soothing. It is suitable for a variety of skin types, especially for those who have the needs of anti-aging, whitening, anti-inflammation, and for those with damaged skin barriers.
