Thymosin
It is used to treat various infectious diseases caused by viruses, bacteria, etc., such as chronic hepatitis B, herpes zoster, influenza, etc. It can enhance the body's immune defense ability, help the body eliminate pathogens, shorten the course of the disease, relieve symptoms, and reduce the recurrence rate of infections. In the comprehensive treatment of tumors, thymosin can be used as an adjuvant therapeutic drug. It can improve the immune function of tumor patients, enhance the body's ability to recognize and kill tumor cells, reduce adverse reactions such as immune deficiency caused by chemotherapy and radiotherapy, improve the quality of life of patients, and prolong the survival period. For some autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus, etc., thymosin can regulate the immune function, correct immune disorders, reduce the inflammatory response, relieve disease symptoms, and slow down the progression of the disease. It is suitable for primary or secondary immunodeficiency diseases, such as immunodeficiency caused by congenital thymic hypoplasia, AIDS, etc. It can improve the immune status of patients, enhance the body's resistance to various pathogens, and reduce the occurrence of complications such as infections.
Thymosin α1
- Molecular Formula: C₁₃₉H₂₁₃N₃₅O₅₁
- Molecular Weight: 3108.4
- Isoelectric Point: Approximately 4.2
- Characteristics of Amino Acid Sequence: Composed of 28 amino acids, the acetylation modification at the N-terminus plays an important role in its biological activity and stability. It contains multiple acidic amino acids (such as Asp, Glu) and basic amino acids (such as Lys) inside. This characteristic of amino acid composition helps it interact with various cell surface receptors or other biomolecules.
Thymosin β4
- Molecular Formula: C₂₀₇H₃₂₉N₅₉O₆₂
- Molecular Weight: 4966.2
- Isoelectric Point: Approximately 4.3
- Characteristics of Amino Acid Sequence: Composed of 43 amino acid residues, it contains multiple proline residues. These proline residues can affect the conformation of the peptide chain, endowing thymosin β4 with a specific spatial structure, which is conducive to its exertion of biological functions. There are also some charged amino acids in its sequence, which can participate in electrostatic interactions with other molecules.
